Tepezza is a biologic therapy that is indicated to treat:

• Thyroid Eye Disease (TED)

What Is Tepezza?  

Tepezza (teprotumumab-trbw) is a prescription medication administered for patients in all IV LEAGUE INFUSION SERVICES centers via IV infusion. 

How Tepezza Works  

 Tepezza works by targeting and blocking the activation and signaling of insulin-like growth factor1 receptor (IGF-1R), which can reduce symptoms of thyroid eye disease. 

Doctors order teprotumumab-trbw to treat: 

• Thyroid Eye Disease (TED) 

Tepezza Infusion Dosage and Administration  

Patients receive teprotumumab-trbw intravenously. Treatment time for a Tepezza infusion at a medical clinic like IV LEAGUE INFUSION SERVICES Health usually lasts between 60 and 90 minutes. 

Dosage and Frequency  

Before receiving their first intravenous infusion of teprotumumab-trbw, the ordering physician determines the patient’s dose. This dose depends on the patient’s weight as well as the severity of the condition for which he or she is receiving treatment. 

 The therapy regimen for Tepezza consists of a total of eight infusions over twenty-one weeks, equaling one infusion every three weeks. 

Administering Tepezza via IV Infusion  

1.  The nurse prepares the patient’s arm by using rubbing alcohol to sterilize the location that is being used to insert the IV needle. 
2. Following needle insertion, the IV line is held in place with tape. 
3. The nurse attaches the patient’s IV line to the line coming down from the bag of medication. 

Every half-an-hour, the patient’s nurse takes his or her vitals.

Tepezza Infusion Side Effects  

As with all medications, side effects are possible.  

The most common side effects of tepezza include: 

• Muscle cramps or spasms 
• Nausea 
• Hair loss 
• Diarrhea 
• Feeling tired 
• High blood sugar 
• Hearing problems 
• Taste changes 
• Headache 
• Dry skin 

Infusion-related reactions are also possible when being treated with Tepezza. 

How To Prepare for a Tepezza Infusion  

It is essential that patients inform their physician if they: 

• Have an inflammatory bowel disease (Crohn’s disease or ulcerative colitis) 
• Have diabetes or high blood sugar 
• Are currently taking any medications 

Before treatment, patients should get a good night’s sleep. In addition, they need to drink an adequate amount of fluid and eat a meal before their Tepezza IV infusion treatment at IV LEAGUE INFUSION SERVICES. 

How to Get a Referral for Tepezza IV Infusions  

Every Tepezza referral must be accompanied by a physician’s order for treatment. 

• Patient information should include: 
• Name 
• Current address 
• Home and mobile phone number 
• Insurance information 

Information the physician must include on the patient’s order for Tepezza IV therapy: 

• Patient’s name and DOB 
• Order date 
• Diagnosis 
• Physician’s name and NPI# 
• Office address, phone, and fax numbers 
• Provider’s signature 

Supporting clinical documentation from the physician should include: 

• List of current medications and surgical procedures used to treat condition 
• Patient’s current weight and height 
• Clinical activity score (CAS) for the patient, based on medical policy 
• Clinicals to support patient has Thyroid Eye Disease (TED) 

If you or someone you care about has one of the conditions that Tepezza infusions treat, you may want to learn more about IV infusion treatments with teprotumumab-trbw. To find an IV LEAGUE INFUSION SERVICES infusion center near you, please click here. 

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